In the realm of pharmaceutical research and development, understanding how compounds move across biological membranes is crucial. The Caco-2 permeability assay emerges as a pivotal technique for assessing the intestinal absorption of drug candidates, providing insights into their ...Learn More

Kupffer cells, the resident macrophages of the liver, play a critical role in maintaining hepatic homeostasis and responding to various physiological and pathological stimuli. Their unique position within the liver allows them to interact with numerous cell types and participate ...Learn More

Mouse renal glomerular endothelial cells (mGECs) are specialized cell types located within the glomeruli of the kidney, playing a pivotal role in renal function and homeostasis. Their unique morphological and functional characteristics contribute to the regulation of filtration ...Learn More

Aging of the population and better survival of patients affected by coronary heart disease have led to an increasing number of patients with chronic heart failure, the common end stage of virtually all cardiac diseases. In addition, heart failure is a frequent complication of ...Learn More

The blood-brain barrier (BBB) is formed by endothelial cells of cerebral capillaries and microvessels, coming in close contact with neighboring pericytes and glial cells. As an active interface between the circulation and the central nervous system (CNS), the BBB strictly controls ...Learn More