Michael. Potente

Dr. Michael Potente obtained MD degree from Goethe-University, Frankfurt in 2003, and he then received postdoctoral training there with S. Dimmeler. Dr. Potente is currently leading a research group with a research focus on the blood vessels, at the Max Planck Institute got Heart and Lung Research, Bad Nauheim. Dr. Potente and his lab group are interested in the regulatory mechanisms that governs the metabolisms of the endothelial cells, as the vessels are developed from endothelial cells, under angiogenic signals. In addition, the group is searching for the moflecular sensors employed by the endothelial cells, which aid them adapt behaviour to oxygen and nutrient availability. They aim to understand how endothelial metabolic state controls vessel growth and function, and how deregulation contributes to disease.

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Max Planck Institute for Heart and Lung ResearchAngiogenesis & Metabolism Laboratory

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Angiogenesis 0 Microscopy 0 Cell Metabolism 0 Endothelial Cells 0 Developmental Biology 0

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  1. Fukuda R, Aharonov A, Ong YT, et al. Metabolic modulation regulates cardiac wall morphogenesis in zebrafish. Elife. 2019;8:e50161. Published 2019 Dec 23. doi:10.7554/eLife.50161

  2. Riddell M, Nakayama A, Hikita T, et al. aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability. Nat Commun. 2018;9(1):5357. Published 2018 Dec 17. doi:10.1038/s41467-018-07739-0

  3. Stone OA, El-Brolosy M, Wilhelm K, et al. Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. Nat Commun. 2018;9(1):4077. Published 2018 Oct 9. doi:10.1038/s41467-018-06406-8

  4. Herz K, Becker A, Shi C, et al. Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system. Angiogenesis. 2018;21(2):349-361. doi:10.1007/s10456-018-9601-1

  5. Neto F, Klaus-Bergmann A, Ong YT, et al. YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development. Elife. 2018;7:e31037. Published 2018 Feb 5. doi:10.7554/eLife.31037


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