Jijie Chai

The main interest of Chai’s laboratory is focused on structural and functional studies of biologically and medically important macromolecules, mainly through protein crystallography, in couple with biochemical, biological and other approaches, to gain insights into structure-function relationship of these macromolecules. The Chai Lab collaborates with the groups within National Institute of Biological Sciences, and several joint projects have been initiated. Specifically, one line of the research has a emphasis on the elucidation the molecular mechanisms underlying transcription regulation by covalent histone modifications, especially histone methylation. Another project the lab is currently interested in is about pathogen-host interaction. The long-term goal of Chai and his team is to investigate the structure-function relationship of protein involved in these two fields.

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Tsinghua University

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Structure and Functions of Macromolecules 0 Molecular Mechanisms of Transcription Regulation 0 Host-Microbe Interaction 0 Microscopic Techniques 0

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