KR-12 amide (human)

Description:

KR-12 is 18-29 amino acid residuesof LL-37 and is the smallest peptide of LL-37 retaining antibacterial activity. KR12 displays a selective toxic effect on bacteria but not on human cells. It may be used as a template for developing novel antimicrobial agents of therapeutic use.

Sequence:

KRIVQRIKDFLR-NH₂

General

References

Comments (0)

Name	KR-12 amide (human)
Category	Antimicrobial and Related Peptides
One Letter Code	KRIVQRIKDFLR-NH₂
Three Letter Code	{Lys}{Arg}{Ile}{Val}{Gln}{Arg}{Ile}{Lys}{Asp}{Phe}{Leu}{Arg}-NH₂
Molecular Weight	1570.950
Application	Antimicrobial & Antiviral Peptides

Wang, Guangshun. "Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles." Journal of Biological Chemistry 283.47 (2008): 32637-32643.