There are three main types of vaccines; live-attenuated, inactivated, and subunit vaccines. Live-attenuated vaccines work by weakening the original pathogen. Inactivated vaccines are killed pathogens. Subunit vaccines are one part of the original pathogen, which we call antigen. Antigens trigger the immune response to the pathogen.
To develop vaccines, researchers have to isolate and purify the viral material in order to ensure that the material is free of impurities. Then, depending on which vaccine type they are trying to make, they will either kill or weaken the pathogen by destroying some viral DNA in order to prevent viral replication. One bottleneck in the development of vaccines is the rate at which the virus mutates. Since the virus mutates fast, it is hard to keep up with a standard vaccine. Another problem is the increase in vaccine prices. Although there are next-generation vaccine development research going on now, the price of vaccines has been plummeting.
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