#Everyone is a writer

Chimeric antigen receptor (CAR) T cell therapy is one of the approaches of cancer treatment, which uses T cells engineered with CARs for cancer therapy.

Principles

CAR- T cells are T cells that have been genetically engineered to produce an artificial T-cell receptor for use in immunotherapy. The CAR-T cells are able to bind to an antigen on the cancer cells and kill them.

Advantages

The initial clinical remission rates after CAR-T cell therapy in all patients are as high as 90%.

Disadvantages

Little data about the long-term effects of CAR-T cell therapy; adverse effects including cytokine release syndrome and neurological toxicity.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582407/

https://www.labiotech.eu/car-t/car-t-therapy-cancer-review/