Shuo Huang
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Nanjing University - Biomimetic Nanotechnology Lab
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DNA sequencing 1 Nanopore 1 Bionanotechnology 1
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Neutralizing antibodies (NAbs) are critical human immune defense mechanisms against viral infections. NAbs can bind to sites on the virus and inhibit entry of that virus into the host. It is a key parameter to evaluate COVID-19 vaccine efficacy per Guidelines from Development and ...Learn More
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This 3D animation shows you how DNA is copied in a cell. It shows how both strands of the DNA helix are unzipped and copied to produce two identical DNA molecules. TranscriptDNA is a molecule made up of two strands twisted around each other in a double helix shape. Each strand is ...Learn More
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Wang, S.; Cao, J.; Jia, W.; Guo, W.; Yan, S.; Wang, Y.; Zhang, P.; Chen, H.-Y. *; Huang, S.*, Single molecule observation of hard–soft-acid–base (HSAB) interaction in engineered Mycobacterium smegmatis porin A (MspA) nanopores. Chemical Science 2020. DOI: 10.1039/C9SC05260G
Cao, J.; Jia, W.; Zhang, J.; Xu, X.; Yan, S.; Wang, Y.; Zhang, P.; Chen, H.-Y.; Huang, S.*, Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore. Nature Communications 2019, 10 (1), 5668.
Wang, Y. Q.; Wang, Y.; Du, X. Y.; Yan, S. H.; Zhang, P. K.; Chen, H. Y.*; Huang, S.*, Electrode-free nanopore sensing by DiffusiOptoPhysiology. Science Advances 2019, 5.
Wang, Y.#; Patil, K. M.#; Yan, S. H.; Zhang, P. K.; Guo, W. M.; Wang, Y. Q.; Chen, H. Y.; Gillingham, D.*; Huang, S.*, Nanopore Sequencing Accurately Identifies the Mutagenic DNA Lesion O6-Carboxymethyl Guanine and Reveals Its Behavior in Replication. Angewandte Chemie International Edition 2019, 58 (25), 8432-8436. ( #These authors contribute equally)
Yan, S. H. #; Li, X. T. #*; Zhang, P. K.; Wang, Y. Q.; Chen, H. Y.; Huang, S.*; Yu, H. Y.*, Direct sequencing of 2′-deoxy-2′-fluoroarabinonucleic acid (FANA) using nanopore-induced phase-shift sequencing (NIPSS). Chemical Science 2019, 10 (10), 3110-3117. ( #These authors contribute equally)
Wang, Y. Q.; Yan, S. H.; Zhang, P. K.; Zeng, Z. D.; Zhao, D.; Wang, J. X.; Chen, H. Y.*; Huang, S.*, Osmosis-Driven Motion-Type Modulation of Biological Nanopores for Parallel Optical Nucleic Acid Sensing. ACS Applied Materials & Interfaces 2018, 10 (9), 7788-7797.
Huang, S.#; Romero-Ruiz, M.#; Castell, O. K.; Bayley, H.; Wallace, M. I.*, High-throughput optical sensing of nucleic acids in a nanopore array. Nature Nanotechnology 2015, 10, 986. ( #These authors contribute equally)
Huang, S.; He, J.; Chang, S.; Zhang, P. M.; Liang, F.; Li, S. Q.; Tuchband, M.; Fuhrmann, A.; Ros, R.; Lindsay, S.*, Identifying single bases in a DNA oligomer with electron tunnelling. Nature Nanotechnology 2010, 5 (12), 868-873.
Huang, S.; Chang, S.; He, J.; Zhang, P. M.; Liang, F.; Tuchband, M.; Li, S. Q.; Lindsay, S.*, Recognition Tunneling Measurement of the Conductance of DNA Bases Embedded in Self-Assembled Monolayers. The Journal of Physical Chemistry C 2010, 114 (48), 20443-20448.
Huang, S.*, Nanopore-based sensing devices and applications to genome sequencing: a brief history and the missing pieces. Chinese science bulletin 2014, 59 (35), 4918-4928.
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