Juan Anguita

Dr. Juan Anguita joined CIC bioGUNE as an Ikerbasque Professor in 2012. He has a BS degree in Biochemistry and Molecular Biology from the University of the Basque Country, and a PhD degree in Animal Health from the University of Leon. After 5 years as a postdoctoral fellow at Yale University School of medicine followed by 2 years as Associate Research Scientist (non-tenure faculty position) at the same institution, Dr. Anguita started his independent career fi rst as an Assistant Professor in the Department of Biology at the University of North Carolina at Charlotte, then as an Assistant and then Associate Professor with tenure in the Department of Veterinary and Animal Sciences at the University of Massachusetts at Amherst. Dr. Anguita´s laboratory is currently focused on the study of the mammalian host immune response to the spirochete that causes Lyme disease, Borrelia burgdorferi. His work is centered in the mechanisms of immune defense against infection, particularly focused on the phagocytosis of spirochetes and the activation of macrophages in the context of cardiac infection. His laboratory is also involved in the search of vaccine candidates to tick salivary antigens in order to prevent the transmission of several pathogens of medical importance, as part of international collaborative networks that include ANTIDotE, an European Commission funded consortium. Dr. Anguita’s group performs extensive –omic analysis relevant to his research interests, including phosphoproteomics, transcriptomics, proteomics and metabolomics.

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CIC bioGUNE (Spain)

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  1. Kalscheuer R, Palacios A, Anso I, et al. The capsule: a cell structure with key implications in pathogenesis Biochem. J.. 2019; 476(14):1995-2016.

  2. Palacios A, Sampedro L, Sevilla IA, et al. Mycobacterium tuberculosis extracellular vesicle-associated lipoprotein LpqH as a potential biomarker to distinguish paratuberculosis infection or vaccination from tuberculosis infection. BMC veterinary research. 2019; 15(1):188

  3. Rego ROM, Trentelman JJA, Anguita J, et al. Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission Parasites Vectors. 2019; 12(1).


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