Dr. Shao is an Investigator and Deputy Director for Academic Affairs National Institute of Bilogical Sciences, Beijing, China. Recently, he showed that caspase-11, 4 and 5 are cytosolic immune receptors for LPS and activated by direct binding to its lipid A part. Like caspase-1 a More...
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Zhou P, She Y, Dong N, et al. Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose. Nature. 2018;561(7721):122-126.
Xu Y, Zhou P, Cheng S, Lu Q, Nowak K, Hopp A, Li L, Shi X, Zhou Z, Gao W, Li D, He H, Liu X, Ding J, Hottiger M, Shao F. (2019) A Bacterial effector reveals the V-ATPase-ATG16L1 axis that initiates xenophagy, Cell, 178, 1-15.
Zhou P, She Y, Dong N, Li P, He H, Borio A, Wu Q, Lu S, Ding X, Cao Y, Xu Y, Gao W, Dong M, Ding J, Wang DC, Zamyatina A, Shao F. (2018) Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose, Nature, 561, 122-126 (Published online Aug 15).
Li P, Jiang W, Yu Q, Liu W, Zhou P, Li J, Xu J, Xu B, Wang F & Shao F. (2017) Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defense, Nature, 551, 378-383 (Published online Oct 11).
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